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Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a condition where a woman’s ovaries stop working normally before the age of 40.

In the United States, POI affects approximately 1% of women under the age of 40. This means that roughly 1 in 100 women will experience POI by the time they turn 40.

POI can affect a woman’s fertility, mental health, bone health, and cardiovascular health